Jay P McLaughlin Selected Research

1-benzylpiperazine

1/2021

Development of New Benzylpiperazine Derivatives as σ1 Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects.

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Jay P McLaughlin Research Topics

Disease

17	Pain (Aches) 06/2022 - 06/2009
8	Hyperalgesia 06/2022 - 05/2004
8	Neuralgia (Stump Neuralgia) 06/2022 - 05/2004
8	Respiratory Insufficiency (Respiratory Failure) 01/2021 - 06/2009
7	Chronic Pain 06/2022 - 01/2019
6	Neurocognitive Disorders (Clerambault Syndrome) 01/2021 - 01/2015
4	Substance-Related Disorders (Drug Abuse) 01/2022 - 06/2009
4	HIV Infections (HIV Infection) 02/2021 - 01/2014
4	Constipation 01/2021 - 04/2013
3	Infections 01/2021 - 06/2013
3	Cocaine-Related Disorders (Cocaine Addiction) 01/2021 - 07/2002
2	Memory Disorders (Memory Loss) 01/2022 - 04/2012
2	Dementia (Dementias) 10/2021 - 01/2015
2	Alcoholism (Alcohol Abuse) 01/2021 - 06/2012
2	Inflammation (Inflammations) 01/2021 - 01/2021
2	Opioid-Related Disorders (Opiate Addiction) 11/2020 - 01/2020
2	Neuroinflammatory Diseases 09/2015 - 01/2015
1	Pruritus (Itching) 01/2022
1	Mood Disorders (Mood Disorder) 01/2022
1	Substance Withdrawal Syndrome (Withdrawal Symptoms) 11/2021
1	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2021
1	Binge Drinking 01/2021
1	Disease Progression 01/2021
1	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 09/2014
1	Cognitive Dysfunction 06/2012

Drug/Important Bio-Agent (IBA)

10	Opioid Analgesics (Opioids)IBA 01/2022 - 05/2004
8	Morphine (MS Contin)FDA LinkGeneric 07/2021 - 06/2009
7	Analgesics (Analgesic Drugs)IBA 06/2022 - 06/2015
6	tat Gene Products (tat Protein)IBA 06/2022 - 01/2014
5	LigandsIBA 06/2022 - 06/2012
5	Cocaine (Cocaine HCl)IBA 02/2021 - 09/2014
4	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2014
3	sigma-2 receptorIBA 06/2022 - 01/2019
3	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 01/2022 - 09/2014
3	Pharmaceutical PreparationsIBA 07/2021 - 01/2020
3	Formaldehyde (Formol)FDA Link 01/2021 - 01/2019
3	Trans-Activators (Trans-Acting Factor)IBA 01/2021 - 06/2013
3	Opioid Receptors (Opioid Receptor)IBA 04/2013 - 05/2004
2	Gabapentin (Neurontin)FDA LinkGeneric 06/2022 - 01/2019
2	sigma Receptors (sigma Receptor)IBA 06/2022 - 01/2019
2	Human Immunodeficiency Virus tat Gene ProductsIBA 06/2022 - 04/2012
2	CJ 15,208IBA 01/2022 - 01/2020
2	kappa Opioid Receptors (kappa Opioid Receptor)IBA 01/2022 - 06/2012
2	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 01/2019
2	TeaIBA 07/2021 - 11/2020
2	Dynorphins (Dynorphin)IBA 06/2012 - 05/2004
1	Doxycycline (Periostat)FDA LinkGeneric 06/2022
1	Dimethyl FumarateIBA 06/2022
1	AntioxidantsIBA 06/2022
1	Indomethacin (Indometacin)FDA LinkGeneric 06/2022
1	Sucrose (Saccharose)IBA 06/2022
1	dimethyl sulfone (methylsulfonylmethane)IBA 06/2022
1	Sigma-1 ReceptorIBA 01/2022
1	Amino Acids FDA Link 01/2022
1	ChromatinIBA 01/2022
1	Histones (Histone)IBA 01/2022
1	Lysine (L-Lysine)FDA Link 01/2022
1	Tyrosine (L-Tyrosine)FDA Link 01/2022
1	Opioid Peptides (Opioid Peptide)IBA 01/2022
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2022
1	Biomarkers (Surrogate Marker)IBA 10/2021
1	AlkaloidsIBA 07/2021
1	mitragynine pseudoindoxylIBA 07/2021
1	mitragynineIBA 07/2021
1	Taurine FDA Link 01/2021
1	Ethanol (Ethyl Alcohol)IBA 01/2021
1	1-benzylpiperazineIBA 01/2021
1	BMS-986122IBA 01/2021
1	Mitochondrial DNA (mtDNA)IBA 01/2021
1	Biological ProductsIBA 01/2021
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2021
1	Glutathione (Reduced Glutathione)IBA 01/2021
1	corynoxineIBA 01/2021
1	hirsutineIBA 01/2021
1	ArrestinIBA 01/2021
1	Therapeutic UsesIBA 11/2020
1	Dopamine (Intropin)FDA LinkGeneric 01/2020
1	VincamineIBA 01/2020
1	3- (2- ((cyclobutylmethyl)(phenethyl)amino)ethyl)phenolIBA 01/2017
1	delta Opioid Receptors (delta Opioid Receptor)IBA 11/2015
1	Human Immunodeficiency Virus ProteinsIBA 09/2015
1	didehydro-cortistatin AIBA 01/2015
1	Methamphetamine (Desoxyn)FDA LinkGeneric 01/2015
1	NeuropeptidesIBA 11/2014
1	phenylalanyl- leucyl- phenylalanyl- glutaminyl- prolyl- glutaminyl- arginyl- phenylalaninamideIBA 11/2014
1	galleinIBA 04/2013
1	Narcotics (Narcotic Analgesics)IBA 06/2009
1	mu Opioid Receptors (mu Opioid Receptor)IBA 06/2009
1	8-carboxamidocyclazocineIBA 07/2002
1	BenzomorphansIBA 07/2002

Therapy/Procedure

11	Therapeutics 06/2022 - 07/2002
2	Analgesia 01/2021 - 01/2021
1	Injections 06/2022
1	Ligation 05/2004